منابع مشابه
The Arrangement of Genes in Drosophila Virilis.
cism misses the mark. It need only be stated that Castle was wrong in supposing that the cross-overs between yellow and white should be subtracted from the total before the white bifid cross-over value is calculated. If, as Castle states, he cannot conceive of a mechanism "which would tie two genes together in such a way that they will subsequently separate from each other oftener than they wil...
متن کاملChromosomal arrangement of leghemoglobin genes in soybean.
A cluster of four different leghemoglobin (Lb) genes was isolated from AluI-HaeIII and EcoRI genomic libraries of soybean in a set of overlapping clones which together include 45 kilobases (kb) of contiguous DNA. These four genes, including a pseudogene, are present in the same orientation and are arranged in the order: 5'-Lba-Lbc1-Lb psi-Lbc3-3'. The intergenic regions average 2.5 kb. In addit...
متن کاملFunctional Immunoglobulin Light Chain Genes
Rearrangement of Ig genes proceeds during B cell differentiation in an orderly fashion. First the heavy (H) chain gene is rearranged in pre-B cells . These cells can express cytoplasmic A chain but no light (L) chain (1). The K light chain genes rear range next and if they fail to produce a functional gene on either chromosome the X light chain genes are rearranged (2) . It is generally believe...
متن کاملThe organization and diversity of immunoglobulin genes.
We have used purified mouse immunoglobulin light chain mRNA and synthetic DNA which is complementary to it to assess the reiteration frequency of gene sequences corresponding to the kappa constant region of the mouse immunoglobulin light chain. These studies indicate that the constant region sequence is represented only two to three times per haploid mouse genome, a finding that rules out a sim...
متن کاملLinkage arrangement of human placental lactogen and growth hormone genes.
Human placental lactogen (hPL) and growth hormone (hGH) are two hormones thought to have evolved from a common ancestral gene (along with prolactin), yet they have quite different functions and specificities. The nucleic acid sequences of the respective cDNAs of the two genes share considerable homology, as well as the existence of multiple forms of each gene within the genome. In this study we...
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ژورنال
عنوان ژورنال: Nature
سال: 1976
ISSN: 0028-0836,1476-4687
DOI: 10.1038/264699a0